1.  People will randomly yell Snakes on a Plane.  This isn’t that funny, but put it up with it in the begining and it’ll die down once people get into the movie.

2.  The movie is solid entertainment, but it isn’t perfection.  It could have been improved in nearly every aspect.  Think of it this way: Snakes on a Plane is like a good episode of the Simpsons from one of its recent seasons.  It gets the job done and does everything you could expect, but it is a far cry from the utter perfection of higher quality work, like any episode of Arrested Development.

3.  Laugh whenever you want.  Most people will laugh at the obvious things - but just because other people aren’t laughing, doesn’t mean it isn’t hilarious.  I for one was laughing for close to 3 minutes after a snake, upon first being released, lunges at a cluster of wires, ripping them out.

And 4th - and most importantly - if you see it this weekend, pay close attention during the scene when the power gets knocked out on the plane.  I, and everyone I went with, weren’t able to tell if it was from the actual movie, or the audience, but someone yelling, "THE SNAKES!" was pure gold and I want to know if it was, in fact, part of the movie.

Oh, and make sure you see it at night with a packed crowd.  It feeds the flames of absurdity until you can’t help but have fun.